ALEXANDRIA, Va., March 19 -- United States Patent no. 12,251,424, issued on March 18, was assigned to Janssen Pharmaceutica NV (Beerse, Belgium).

"Methods of protecting vascular integrity induced by targeted radiation therapy" was invented by Gary Eichenbaum (Belle Mead, N.J.) and Alfred Tonelli (Upper Nyack, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods of protecting vascular integrity in a subject exposed to a targeted radiation therapy are described. In particular, an effective amount of a thrombopoietin (TPO) mimetic, such as TPOm, is used to protect vascular integrity following the radiation therapy."

The patent was filed on July 26, 2018, under Application No. 16/633,854.

*For further i...