US Patent Issued to Janssen Pharmaceutica on Feb. 10 for "Compounds useful as factor XIa inhibitors" (Pennsylvania Inventors)

ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,545,677, issued on Feb. 10, was assigned to Janssen Pharmaceutica NV (Beerse, Belgium).

"Compounds useful as factor XIa inhibitors" was invented by Guozhang Xu (Spring House, Pa.), Mark J. Macielag (Spring House, Pa.), Zhijie Liu (Spring House, Pa.), Tho V. Thieu (Spring House, Pa.) and Ravi Nargund (Spring House, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is directed to Factor XIa inhibitors, tautomers, stereoisomers, isotopologues, and pharmaceutically acceptable salts and solvates thereof, pharmaceutical compositions containing said compounds and the use of said compounds in the treatment and/or prophylaxis of thromboemb...