US Patent Issued to Janssen Biotech on Oct. 28 for "Macrocyclic chelators and methods of use thereof" (Pennsylvania, California Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,453,785, issued on Oct. 28, was assigned to Janssen Biotech Inc. (Horsham, Pa.).

"Macrocyclic chelators and methods of use thereof" was invented by Rhys Salter (Doylestown, Pa.), Vadim Dudkin (Chalfont, Pa.), Fengbin Song (Doylestown, Pa.), Wei Zhang (Malvern, Pa.), Shalom Goldberg (Merion Station, Pa.) and John Keith (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Macrocyclic chelators for chelation of alpha-emitting radiometal ions, such as actinium-225 are provided. Also provided are radiometal complexes containing an alpha-emitting radiometal ion bound to the macrocyclic chelator via coordinate bonding, and radioimmunoconjugates containing...