ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,441,985, issued on Oct. 14, was assigned to Janssen Biotech Inc. (Horsham, Pa.).

"Methods for making insulin in vivo" was invented by Jean Xu (Skillman, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides methods to promote the differentiation of pluripotent stem cells into insulin producing cells. In particular, the present invention provides a method to produce cells expressing markers characteristic of the pancreatic endocrine lineage that co-express NKX6.1 and insulin and minimal amounts of glucagon."

The patent was filed on Jan. 20, 2023, under Application No. 18/099,852.

*For further information, including images, ...