ALEXANDRIA, Va., June 9 -- United States Patent no. 12,285,468, issued on April 29, was assigned to IPSEN BIOPHARM Ltd. (Wrexham, Great Britain).

"Liquid neurotoxin formulation stabilized with tryptophan or tyrosine" was invented by Anders Jarstad (Uppsala, Sweden), Anna Friis (Uppsala, Sweden), Ulf Stahl (Uppsala, Sweden), Ann Gurell (Stockholm), Barbro Agren (Mattmar, Sweden), Emilia Edstrom (Uppsala, Sweden) and Andrew Pickett (Uppsala, Sweden).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to stable liquid neurotoxin formulations which are free of animal proteins, comprising a surfactant, an amino acid selected from tryptophan and tyrosine, a buffer comprising sodium, chloride and ph...