US Patent Issued to Ionis Pharmaceuticals on March 4 for "Compounds and methods for reducing LRRK2 expression" (California Inventors)

ALEXANDRIA, Va., March 5 -- United States Patent no. 12,241,067, issued on March 4, was assigned to Ionis Pharmaceuticals Inc. (Carlsbad, Calif.).

"Compounds and methods for reducing LRRK2 expression" was invented by Tracy A. Cole (Encintas, Calif.) and Susan M. Freier (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are compounds, methods, and pharmaceutical compositions for reducing the amount or activity of LRRK2 RNA in a cell or animal, and in certain instances reducing the amount of LRRK2 protein in a cell or animal. Such compounds, methods, and pharmaceutical compositions are useful to ameliorate at least one symptom or hallmark of a neurodegenerative disease. Such symptoms and hallma...