US Patent Issued to Ionis Pharmaceuticals on July 8 for "Compounds and methods for reducing ATXN3 expression" (California Inventors)

ALEXANDRIA, Va., July 9 -- United States Patent no. 12,350,285, issued on July 8, was assigned to Ionis Pharmaceuticals Inc. (Carlsbad, Calif.).

"Compounds and methods for reducing ATXN3 expression" was invented by Susan M. Freier (San Diego) and Holly Kordasiewicz (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are compounds, methods, and pharmaceutical compositions for reducing the amount or activity of ATXN3 mRNA in a cell or animal, and in certain instances reducing the amount of Ataxin-3 protein in a cell or animal. Such compounds, methods, and pharmaceutical compositions are useful to prevent or ameliorate at least one symptom or hallmark of a neurodegenerative disease. Such symptoms...