ALEXANDRIA, Va., July 3 -- United States Patent no. 12,343,357, issued on July 1, was assigned to Ionis Pharmaceuticals Inc. (Carlsbad, Calif.).

"Compositions and methods for modulating MECP2 expression" was invented by Susan M. Freier (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are compounds and methods for decreasing MECP2 mRNA and protein expression. Such compounds and methods are useful to treat, prevent, or ameliorate MECP2 associated disorders and syndromes. Such MECP2 associated disorders include MECP2 duplication syndrome."

The patent was filed on Aug. 23, 2021, under Application No. 17/408,920.

*For further information, including images, charts and tables, please vis...