US Patent Issued to Ionis Pharmaceuticals on Dec. 30 for "Compositions and methods for modulating apolipoprotein C-III expression" (California Inventors)

ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,509,684, issued on Dec. 30, was assigned to Ionis Pharmaceuticals Inc. (Carlsbad, Calif.).

"Compositions and methods for modulating apolipoprotein C-III expression" was invented by Thazha P. Prakash (Carlsbad, Calif.), Punit P. Seth (Carlsbad, Calif.), Eric E. Swayze (Encinitas, Calif.) and Mark J. Graham (San Clemente, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are oligomeric compounds with conjugate groups targeting apoplipoprotein C-III (ApoCIII). In certain embodiments, the ApoCIII targeting oligomeric compounds are conjugated to N-Acetylgalactosamine. Also disclosed herein are conjugated oligomeric compounds targeting Apo...