ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,440,578, issued on Oct. 14, was assigned to IO BIOSCIENCES INC. (Chalfont, Pa.).
"Nucleic acid constructs comprising gene editing multi-sites and uses thereof" was invented by Sicco Hans Popma (Chalfont, Pa.) and Di Zhang (Chalfont, Pa.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein is a polynucleotide construct comprising one or more primary endonuclease recognition sequences upstream and downstream of a multiple gene editing site that comprises a plurality of secondary endonuclease recognition sequences. The primary endonuclease recognition sequences facilitate insertion of the multiple gene editing site into a host cell genome. The s...