ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,478,399, issued on Nov. 25, was assigned to Invera Medical Ltd. (Galway, Ireland).

"Method of treating a blood vessel in a subject" was invented by Sean Cummins (County Limerick, Ireland), Stephen Cox (Westport, Ireland) and Nigel Phelan (County Galway, Ireland).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method of treating a blood vessel in a subject comprises the steps of advancing a catheter device comprising a deployable abrasive element distally across a treatment zone in the vessel, deploying the abrasive element into contact with the vessel wall, actuating the abrasive element to cause disruption of the vessel wall and exposure of subendothel...