ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,478,623, issued on Nov. 25, was assigned to INTRA-CELLULAR THERAPIES INC. (Bedminster, N.J.).

"Methods of treating central nervous system disorders comprising administering lumateperone and a nitric oxide donor" was invented by Robert E. Davis (San Diego), Gretchen Snyder (New York) and Peng Li (New Milford, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure provides methods for the for treatment of psychosis, such as schizophrenia, or depression (such as bipolar depression) and/or anxiety, comprising administering to a patient in need thereof, (i) a 5-HT2A or 5-HT2A/D2 receptor ligand, for example a substituted heterocycle fused gamma-c...