ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,052, issued on June 17, was assigned to INTRA-CELLULAR THERAPIES INC. (Bedminster, N.J.).

"Organic compounds" was invented by Peng Li (New Milford, N.J.), Qiang Zhang (Somerset, N.J.) and Hailin Zheng (New York).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to particular substituted heterocycle fused gamma-carbolines, in free, solid, pharmaceutically acceptable salt and/or substantially pure form as described herein, pharmaceutical compositions thereof, and methods of use in the treatment of diseases involving the 5-HT2A receptor, the serotonin transporter (SERT), pathways involving the dopamine D1 and D2 receptor signaling sys...