US Patent Issued to INTRA-CELLULAR THERAPIES on Aug. 26 for "Organic compounds" (New York, California, New Jersey Inventors)

ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,396,992, issued on Aug. 26, was assigned to INTRA-CELLULAR THERAPIES INC. (Bedminster, N.J.).

"Organic compounds" was invented by Gretchen Snyder (New York), Lawrence P. Wennogle (Hillsborough, N.J.), Jennifer O'Brien (New York), Joseph Hendrick (New York) and Robert Davis (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure relates to the use of phosphodiesterase 1 (PDE1) inhibitors for the treatment of cancers and tumors, including for inhibiting tumor recruitment of macrophages and other cells to the tumor or cancer, for complementing and enhancing checkpoint inhibitor therapies, and for mitigating the side effects (i.e., inflamma...