US Patent Issued to International Business Machines on Sept. 9 for "Structure-based, ligand activity prediction using binding mode prediction information" (New York, New Jersey Inventors)

ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,412,638, issued on Sept. 9, was assigned to International Business Machines Corp. (Armonk, N.Y.).

"Structure-based, ligand activity prediction using binding mode prediction information" was invented by Joseph Anthony Morrone (Pleasantville, N.Y.), Jeffrey Kurt Weber (Brooklyn, N.Y.), Sugato Bagchi (White Plains, N.Y.) and Wendy Dawn Cornell (Warren, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A system and method for structure-based, small molecule activity prediction using binding mode prediction information. Binding scores between ligands and target molecules, (e.g. proteins, RNA, DNA, lipids, sugars) are first generated using molecular dockin...