US Patent Issued to Interius Biotherapeutics on March 18 for "Mutated polypeptides, compositions comprising the same, and uses thereof" (Pennsylvania Inventors)

ALEXANDRIA, Va., March 19 -- United States Patent no. 12,252,512, issued on March 18, was assigned to Interius Biotherapeutics Inc. (Philadelphia).

"Mutated polypeptides, compositions comprising the same, and uses thereof" was invented by Bruce C. Schnepp (Havertown, Pa.) and Philip R. Johnson (Bryn Mawr, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided for herein are viral particles comprising a heterologous viral glycoprotein and a targeting moiety, wherein the targeting moiety comprises a polypeptide comprising a formula of T-S1, wherein T is a target binding domain and S1 is a stalk portion. The stalk portion may comprise a variant Fe domain. The stalk portion may comprise a flexible polypepti...