US Patent Issued to Intellia Therapeutics on Nov. 4 for "Compositions and methods for treating alpha-1 antitrypsin deficiency" (Massachusetts Inventors)

ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,460,205, issued on Nov. 4, was assigned to Intellia Therapeutics Inc. (Cambridge, Mass.).

"Compositions and methods for treating alpha-1 antitrypsin deficiency" was invented by Shobu Odate (Arlington, Mass.), Walter Strapps (Dedham, Mass.) and Reynald Michael Lescarbeau (Medford, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods for introducing double-stranded breaks within the SERPINA1 gene are provided. Compositions and methods for reducing and eliminating mutant forms of Alpha1-antitrypsin (AAT), such as seen in subjects having Alpha1-antitrypsin deficiency (AATD), are provided."

The patent was filed on Dec. 9, 2022, under...