US Patent Issued to INTEGRATED MICRO-CHROMATOGRAPHY SYSTEMS on March 18 for "Chimeric and other variant Beta-glucuronidase enzymes with enhanced properties" (South Carolina Inventors)

ALEXANDRIA, Va., March 19 -- United States Patent no. 12,252,719, issued on March 18, was assigned to INTEGRATED MICRO-CHROMATOGRAPHY SYSTEMS INC. (Irmo, S.C.).

"Chimeric and other variant Beta-glucuronidase enzymes with enhanced properties" was invented by Caleb Reece Schlachter (Irmo, S.C.), John Tomashek (Columbia, S.C.) and Lim Andrew Lee (Columbia, S.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Chimeric and other variant Beta-glucuronidase enzymes with enhanced properties as compared to unmodified enzyme are provided. The enzymes of the invention advantageously exhibit enhanced enzymatic activity, enhanced substrate range, enhanced pH range, enhanced temperature range and/or enhanced enzyme stabili...