US Patent Issued to INTEGRATED DNA TECHNOLOGIES on Oct. 7 for "Reverse transcriptase mutants with increased activity and thermostability" (Iowa Inventors)

ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,435,318, issued on Oct. 7, was assigned to INTEGRATED DNA TECHNOLOGIES INC. (Coralville, Iowa).

"Reverse transcriptase mutants with increased activity and thermostability" was invented by Sarah Franz Beaudoin (Iowa City, Iowa) and Christopher Anthony Vakulskas (North Liberty, Iowa).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure provides Moloney murine leukemia virus (MMLV) reverse transcriptase (RTase) mutants. The disclosure as provides suitable amino acid positions in MMLV RTase for mutagenesis and methods and kits for using MMLV RTase mutants to synthesize cDNA from RNA templates."

The patent was filed on July 20, 2021, under Applicatio...