US Patent Issued to INTEGRATED DNA TECHNOLOGIES on July 8 for "S. pyogenes CAS9 mutant genes and polypeptides encoded by same" (Iowa Inventors)

ALEXANDRIA, Va., July 9 -- United States Patent no. 12,351,799, issued on July 8, was assigned to INTEGRATED DNA TECHNOLOGIES INC. (Coralville, Iowa).

"S. pyogenes CAS9 mutant genes and polypeptides encoded by same" was invented by Christopher Anthony Vakulskas (North Liberty, Iowa), Michael Allen Collingwood (North Liberty, Iowa), Garrett Richard Rettig (Coralville, Iowa) and Mark Aaron Behlke (Coralville, Iowa).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention pertains to mutant Cas9 nucleic acids and proteins for use in CRISPR/Cas endonuclease systems, and their methods of use. In particular, the invention pertains to an isolated mutant Cas9 protein, wherein the isolated mutant Cas9 protein is ...