US Patent Issued to INTEGRATED DNA TECHNOLOGIES on July 22 for "Asymmetric targeted amplification methods" (Michigan Inventors)

ALEXANDRIA, Va., July 23 -- United States Patent no. 12,365,937, issued on July 22, was assigned to INTEGRATED DNA TECHNOLOGIES INC. (Coralville, Iowa).

"Asymmetric targeted amplification methods" was invented by Ashley M. Wood (Ann Arbor, Mich.), Jordan Rosefigura (Ann Arbor, Mich.) and Vladimir Makarov (Ann Arbor, Mich.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides kits and methods for a targeted NGS library workflow comprising a multiplexed PCR for target amplification followed by an indexing PCR for incorporation of NGS adapter sequences. This workflow enables overlapping primer pairs in a single tube for contiguous coverage over target regions, while simultaneously preve...