US Patent Issued to INTEGRATED DNA TECHNOLOGIES on April 1 for "Lachnospiraceae bacterium ND2006 CAS12A mutant genes and polypeptides encoded by same" (Iowa Inventors)

ALEXANDRIA, Va., April 2 -- United States Patent no. 12,264,342, issued on April 1, was assigned to INTEGRATED DNA TECHNOLOGIES INC. (Coralville, Iowa).

"Lachnospiraceae bacterium ND2006 CAS12A mutant genes and polypeptides encoded by same" was invented by Sarah Franz Beaudoin (Iowa City, Iowa), Michael Allen Collingwood (North Liberty, Iowa) and Christopher Anthony Vakulskas (North Liberty, Iowa).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention pertains to mutant Lachnospiraceae bacterium ND2006 (Lb) Cas12a nucleic acids and proteins for use in CRISPR/Cas12a endonuclease systems, and their methods of use. In particular, the invention pertains to an isolated mutant LbCas12a protein, wherein the i...