US Patent Issued to Institute for Systems Biology on March 11 for "Crosslinkers for mass spectrometric identification and quantitation of interacting peptides" (Washington Inventors)

ALEXANDRIA, Va., March 12 -- United States Patent no. 12,247,009, issued on March 11, was assigned to Institute for Systems Biology (Seattle).

"Crosslinkers for mass spectrometric identification and quantitation of interacting peptides" was invented by Jie Luo (Seattle) and Jeff Ranish (Seattle).

According to the abstract* released by the U.S. Patent & Trademark Office: "Crosslinking molecules that permit efficient identification of specifically associated proteins and the sites of crosslinking in biological or other samples include two cleavable bonds that are cleavable under the same conditions as peptide bonds in mass spectrometric determinations. Sets of the invention crosslinkers may be provided with isobaric labels containing report...