US Patent Issued to Institute for Cancer Research on July 1 for "Prodigiosin analogs and methods of use" (Pennsylvania Inventors)

ALEXANDRIA, Va., July 3 -- United States Patent no. 12,344,599, issued on July 1, was assigned to Institute for Cancer Research (Philadelphia).

"Prodigiosin analogs and methods of use" was invented by Wafik S. El-Deiry (Philadelphia) and Xiaobing Tian (Philadelphia).

According to the abstract* released by the U.S. Patent & Trademark Office: "Prodigiosin analogs which reactivate the p53 pathway are provided, as well as compositions of these compounds, and methods for reactivation of the p53 pathway using these compounds are provided. The prodigiosin analogs may be used to treat cancer in which p53 mutation plays a role, including prostate cancer, breast cancer, kidney cancer, ovarian cancer, lymphoma, leukemia, and glioblastoma, among othe...