ALEXANDRIA, Va., April 2 -- United States Patent no. 12,263,143, issued on April 1, was assigned to Institut Pasteur de Montevideo (Montevideo, Uruguay) and University of the Republic (Montevideo, Uruguay).
"Ionic channel modulation as a method for treating tumors through inflammasome activation" was invented by Marcelo Hill Mongabure (Canelones, Uruguay), Sofia Russo Rossi (Montevideo, Uruguay), Mercedes Segovia Duarte (Canelones, Uruguay), Maria Ines Varela Vega (Montevideo, Uruguay) and Pablo Oppezzo Llorens (Canelones, Uruguay).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention presents use of ion channel modulator to manipulate expression of the Tmem176b gene, also known as TORID (TOlerance Rel...