US Patent Issued to INSTITUT PASTEUR, ELIGO BIOSCIENCE on Feb. 4 for "Sequence-specific antimicrobials by blocking DNA repair" (French Inventors)

ALEXANDRIA, Va., Feb. 5 -- United States Patent no. 12,214,022, issued on Feb. 4, was assigned to INSTITUT PASTEUR (Paris) and ELIGO BIOSCIENCE (Paris).

"Sequence-specific antimicrobials by blocking DNA repair" was invented by David Bikard (Paris), Lun Cui (Paris), Xavier Duportet (Paris) and Jesus Fernandez Rodriguez (Paris).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to the improvement of endonuclease-based antimicrobials by blocking DNA repair of double-strand break(s) (DSB(s)) in prokaryotic cells. In this respect, the invention especially concerns a method involving blocking DNA repair after a nucleic acid has been submitted to DSB, in particular by a Clustered Regularly Interspa...