US Patent Issued to Insmed on Jan. 13 for "Large-scale manufacturing methods for aminoglycosides" (New Jersey Inventor)

ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,521,345, issued on Jan. 13, was assigned to Insmed Inc. (Bridgewater, N.J.).

"Large-scale manufacturing methods for aminoglycosides" was invented by Robert Worsham (Bridgewater, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are large-scale manufacturing methods for drug formulations containing an aminoglycoside such as amikacin. The method utilizes mixing a first stream comprising DPPC and cholesterol with a second stream comprising amikacin sulfate at particular flow rates to obtain a drug formulation with a superior encapsulation efficiency. The processes described herein address the need for preparing aminoglycoside drug formula...