ALEXANDRIA, Va., Aug. 20 -- United States Patent no. 12,390,522, issued on Aug. 19, was assigned to INPROTHER APS (Copenhagen, Denmark).
"Nucleic acids encoding human endogenous retrovirus K (HERV-k) envelope proteins containing modified immunosuppressive domains (ISD) and uses thereof" was invented by Peter Holst (Soeborg, Denmark), Christian Thirion (Munich) and Lasse Neukirch (Flensburg, Germany).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to an adenoviral vector capable of encoding a virus-like particle (VLP), said VLP displaying an inactive immune-suppressive domain (ISD). The vaccine of the invention shows an improved immune response from either of both of the response p...