ALEXANDRIA, Va., Feb. 19 -- United States Patent no. 12,227,569, issued on Feb. 18, was assigned to INNATE PHARMA (Marseilles, France).
"Humanized antibodies with increased stability" was invented by Laurent Gauthier (Marseilles, France) and Nicolas Schneider (Marseilles, France).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides antibodies having improved stability. Included are antibodies that are capable of binding to KIR3DL2 polypeptides. The antibodies are suitable for the treatment of disorders characterized by KIR3DL2-expressing cells, particularly CD4+ T cells, including malignancies such as Mycosis Fungoides and Sezary Syndrome, and KIR3DL2-expressing autoimmune disorders."...