US Patent Issued to Indiana University Research and Technology on Nov. 25 for "Artificial antigen-presenting cells and methods for producing and using the same" (Indiana Inventor)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,478,688, issued on Nov. 25, was assigned to Indiana University Research and Technology Corp. (Bloomington, Ind.).

"Artificial antigen-presenting cells and methods for producing and using the same" was invented by Yan Yu (Bloomington, Ind.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are biomimetic Janus particles useful as artificial antigen presenting cells capable of activating T cells in vitro. "Bull's eye" ligand patterns mimicking either the native or reverse organization of the T cell immunological synapse are provided on the surface of nano- or micro-sized particles. Methods for activating T cells in vitro using biomimetic Janu...