ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,114, issued on June 17, was assigned to INDIAN INSTITUTE OF TECHNOLOGY BOMBAY (Mumbai, India).
"Humanized anti-CD19 chimeric antigen receptor, its nucleic acid sequence and its preparation" was invented by Rahul Purwar (Mumbai, India), Alka Dwivedi (Mumbai, India), Atharva Karulkar (Mumbai, India) and Srisathya Srinivasan (Mumbai, India).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to novel humanized anti-CD19chimeric antigen receptor containing an optimized anti-CD19 binding domain effective against the treatment of disease associated with expression of the Cluster of Differentiation 19 protein (CD19), and to a nuclei...