ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,433,939, issued on Oct. 7, was assigned to In3Bio Ltd. (Hamilton, Bermuda).
"Self-assembling synthetic proteins comprising cholera toxin beta subunit" was invented by Keith Alan Charlton (Aberdeen, Great Britain), Erik D'Hondt (Bazel, Belgium) and Daniel T. Verhamme (Aberdeen, Great Britain).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides for a synthetic immunogenic protein for use as an immuno-modulatory agent to enhance mammalian immune reactions towards conjugated protein or peptide containing antigens that are otherwise poorly immunogenic, including but not limited to self-antigens. The chimeric immunogenic proteins of t...