ALEXANDRIA, Va., Feb. 19 -- United States Patent no. 12,226,426, issued on Feb. 18, was assigned to IMPERIAL COLLEGE INNOVATIONS Ltd. (London).
"Combination therapy" was invented by Peter Sarkies (London).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a therapeutic combination for use in treating an infection with a pathogen. The therapeutic combination comprises an aminoglycoside antibiotic; and a nucleic acid monoalkylating agent that substitutes a single nucleotide of a nucleic acid with an alkyl group, wherein the therapeutic combination provides an enhanced suppression of a pathogen when compared with an otherwise identical composition lacking said aminoglycoside antibiotic...