ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,397,065, issued on Aug. 26, was assigned to IMPERIAL COLLEGE INNOVATIONS Ltd. (London).
"Nucleic acids, peptides and methods" was invented by Mark Isalan (London).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are novel nucleic acid molecules which encode novel polypeptides for use in treating polyglutamine diseases such as Huntington's disease. The polypeptides of the invention exhibit reduced immunotoxicity in vivo and may have utility in sustained (mid- or long-term) expression in vivo. Also disclosed are methods for the treatment of polyglutamine diseases, such as Huntington's disease and the use of nucleic acids and polypeptides of ...