US Patent Issued to Impact Therapeutics (Shanghai) on Dec. 9 for "3,5-disubstituted pyrazole compounds as kinase inhibitors and uses thereof" (Chinese Inventors)

ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,492,197, issued on Dec. 9, was assigned to Impact Therapeutics (Shanghai) Inc (Shanghai).

"3,5-disubstituted pyrazole compounds as kinase inhibitors and uses thereof" was invented by Sui Xiong Cai (Shanghai), Ye Edward Tian (Shanghai) and Xiaozhu Wang (Nanjing, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compounds represented by Formula I in which A0-A2, R0-R6, L, Z and Q are defined herein. The compounds of Formula I are CHK 1 inhibitors. Therefore, the compounds can be used to treat diseases, disorders and conditions associated with continuous activation of CHK1 or with high internal DNA damage or injury during DNA replication, such as cancers...