US Patent Issued to Immunomedics on May 27 for "Antibody-drug conjugates and uses thereof" (New Jersey, Florida Inventors)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,310,958, issued on May 27, was assigned to Immunomedics Inc. (Foster City, Calif.).

"Antibody-drug conjugates and uses thereof" was invented by David M. Goldenberg (Delray Beach, Fla.) and Serengulam V. Govindan (Springfield, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to therapeutic immunoconjugates comprising SN-38 attached to an antibody or antigen-binding antibody fragment. The antibody may bind to Trop-2 or CEACAM5 and the immunoconjugate may be administered at a dosage of between 4 mg/kg and 16 mg/kg, preferably 4, 6, 8, 9, 10, 12, or 16 mg/kg. When administered at specified dosages and schedules, the immunoco...