US Patent Issued to IMMUNOGEN on Aug. 19 for "Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof" (Massachusetts Inventor)

ALEXANDRIA, Va., Aug. 20 -- United States Patent no. 12,390,471, issued on Aug. 19, was assigned to IMMUNOGEN INC. (Waltham, Mass.).

"Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof" was invented by Wayne C. Widdison (Belmont, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to novel cell-binding agent-maytansinoid conjugate having a self-immolative peptide linker and more specifically to conjugates of formula (I). The invention also provides novel maytansinoid compounds of formula (II), (III), (IV) or (V). The invention further provides compositions and methods useful for inhibiting abnormal cell growth or treating a proliferative disorder in a ...