ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,252, issued on May 13, was assigned to Immatics Biotechnologies GmbH (Tubingen, Germany).
"T cell receptors with improved pairing" was invented by Sebastian Bunk (Tuebingen, Germany), Dominik Maurer (Moessingen, Germany), Jens Fritsche (Dusslingen, Germany), Claudia Wagner (Tuebingen, Germany), Leonie Alten (Tuebingen, Germany), Franziska Hoffgaard (Tuebingen, Germany) and Mathias Ferber (Paris).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to modified T cell receptor (TCR) Alpha or Beta chains, or heterodimers comprising the same, wherein in the variable domain of said modified Alpha or Beta chain, an amino acid at pos...