US Patent Issued to Illumina on Oct. 14 for "Multi-channel protein voxelization to predict variant pathogenicity using deep convolutional neural networks" (British, American Inventors)

ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,444,482, issued on Oct. 14, was assigned to Illumina Inc. (San Diego).

"Multi-channel protein voxelization to predict variant pathogenicity using deep convolutional neural networks" was invented by Tobias Hamp (Cambridge, Great Britain), Kai-How Farh (Hillsborough, Calif.) and Hong Gao (Palo Alto, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A system includes at least a voxelizer, an alternative allele encoder, an evolutionary conservation encoder, and a convolutional neural network. The voxelizer accesses a three-dimensional structure of a reference amino acid sequence of a protein and fits a three-dimensional grid of voxels on atoms in the th...