US Patent Issued to Illumina on July 29 for "Transposon end compositions and methods for modifying nucleic acids" (Wisconsin Inventors)

ALEXANDRIA, Va., July 30 -- United States Patent no. 12,371,687, issued on July 29, was assigned to Illumina Inc. (San Diego).

"Transposon end compositions and methods for modifying nucleic acids" was invented by Haiying Li Grunenwald (Belleville, Wis.), Nicholas Caruccio (Madison, Wis.), Jerome Jendrisak (Madison, Wis.) and Gary Dahl (Madison, Wis.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides methods, compositions and kits for using a transposase and a transposon end for generating extensive fragmentation and 5'-tagging of double-stranded target DNA in vitro, then using a DNA polymerase for generating 5'- and 3'-tagged single-stranded DNA fragments without performing a PCR a...