US Patent Issued to Illumina on July 22 for "Methods and systems for determining somatic mutation clonality" (California Inventors)

ALEXANDRIA, Va., July 23 -- United States Patent no. 12,367,978, issued on July 22, was assigned to Illumina Inc. (San Diego).

"Methods and systems for determining somatic mutation clonality" was invented by Vitor Ferreira Onuchic (San Diego) and Kristina M. Kruglyak (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Computer implemented methods and computer systems are provided for estimating cancer cell fractions indicating proportions of cancer cells carrying one or more mutations of interest using one or more nucleic acid samples from a subject. The methods and systems provided herein implement processes that use a variational Bayesian mixture model to cluster initial cancer cell fractions and obt...