US Patent Issued to Illumina on Aug. 19 for "Polynucleotide enrichment and amplification using CRISPR-Cas or Argonaute systems" (California Inventors)

ALEXANDRIA, Va., Aug. 20 -- United States Patent no. 12,391,983, issued on Aug. 19, was assigned to Illumina Inc. (San Diego).

"Polynucleotide enrichment and amplification using CRISPR-Cas or Argonaute systems" was invented by Jeffrey G. Mandell (San Diego) and Molly He (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for enriching or amplifying a target nucleic acid including providing a system having a guide nucleic acid, and a Cas or Argonaute protein or a variant thereof. The guide nucleic acid contains a target-specific nucleotide region substantially complementary to a region of the target nucleic acid, and contacting the target nucleic acid with the system to form a complex."

The pa...