US Patent Issued to IDORSIA PHARMACEUTICALS on May 13 for "Crystalline forms of a 4-pyrimidinesulfamide derivative aprocitentan" (Swiss Inventors)

ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,189, issued on May 13, was assigned to IDORSIA PHARMACEUTICALS LTD (Allschwil, Switzerland).

"Crystalline forms of a 4-pyrimidinesulfamide derivative aprocitentan" was invented by Martin Bolli (Allschwil, Switzerland) and Markus Von Raumer (Allschwil, Switzerland).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention concerns novel crystalline forms of {5-(4-bromo-phenyl)-6-[2-(5-bromo-pyrimidin-2-yloxy)-ethoxy]-pyrimidin-4-yl}-sulfamide, processes for the preparation thereof, pharmaceutical compositions comprising said crystalline forms, pharmaceutical compositions prepared from such crystalline forms, and their use as endothelin rece...