US Patent Issued to ICOSAVAX on July 1 for "Protein-based nanoparticle vaccine for metapneumovirus" (Washington Inventors)

ALEXANDRIA, Va., July 3 -- United States Patent no. 12,343,391, issued on July 1, was assigned to ICOSAVAX INC. (Seattle).

"Protein-based nanoparticle vaccine for metapneumovirus" was invented by Andrew Lawrence Feldhaus (Seattle), Douglas Andrew Holtzman (Seattle) and Clancey Buchanan Wolf (Seattle).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are virus-like particle vaccines for human metapneumovirus (hMPV) in which the ectodomain of hMPV F protein is linked to, and thereby displayed on, a symmetric protein-based virus-like particle. For example, the vaccine antigen may be a N-terminal fusion of the ectodomain of hMPV F protein to a protein having a multimerization domain for a one- or two-compon...