ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,421,542, issued on Sept. 23, was assigned to Hummingbird Diagnostics GmbH (Heidelberg, Germany).
"Advanced Dumbell PCR for isomiR detection" was invented by Rastislav Horos (Heidelberg, Germany), Bruno Steinkraus (Hanstedt, Germany) and Carla Bieg-Salazar (Heidelberg, Germany).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a method for the detection of small non-coding RNAs in a sample using sequence-specific structured adapters for the ligation by a double stranded RNA ligase with subsequent cDNA production and quantification. The present invention further relates to a kit for carrying out this method."
The patent was ...