ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,415, issued on May 13, was assigned to Huadao (Shanghai) Biopharma Co. Ltd. (Shanghai).

"Fully enclosed cell culture system" was invented by Xuejun Yu (Shanghai), Peng Xu (Shanghai), Yongjun Fang (Shanghai) and Dongge Feng (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a fully enclosed cell culture system, including at least an incubator, a bioreactor, a gas flow assembly, a liquid flow assembly, a temperature adjustment assembly, and a central controller. The system realizes a thermostatic incubation environment. Cells are incubated by perfusion, and a fully enclosed integrated process from cell activation,...