ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,496,331, issued on Dec. 16, was assigned to Horizon Therapeutics USA Inc. (Deerfield, Ill.).
"Combination therapies of prednisone and uricase molecules and uses thereof" was invented by Jeffrey D. Kent (Deerfield, Ill.) and Brian Lamoreaux (Lake Forest, Ill.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are methods for reducing an antibody response to uricase therapy, improving the treatment of gout, reducing uric acid levels, and preventing and/or delaying infusion reactions. The methods may include administration of a uricase and a steroid as described herein."
The patent was filed on Nov. 10, 2017, under Application No. 16/347,900....