US Patent Issued to Hoffmann-La Roche on March 18 for "Anti-transferrin receptor antibodies with tailored affinity" (German Inventors)

ALEXANDRIA, Va., March 19 -- United States Patent no. 12,252,533, issued on March 18, was assigned to Hoffmann-La Roche Inc. (Little Falls, N.J.).

"Anti-transferrin receptor antibodies with tailored affinity" was invented by Stefan Dengl (Munich), Guy Georges (Habach, Germany), Ulrich Goepfert (Penzberg, Germany), Jens Niewoehner (Munich) and Tilman Schlothauer (Penzberg, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "Herein is reported an anti-transferrin receptor antibody that specifically binds to human transferrin receptor and cynomolgus transferrin receptor, which comprises i) a humanized heavy chain variable domain derived from the heavy chain variable domain of SEQ ID NO: 01, and ii) a humaniz...