US Patent Issued to HOFFMANN-LA ROCHE on June 24 for "Method for increasing the specific production rate of eukaryotic cells" (German Inventor)

ALEXANDRIA, Va., June 25 -- United States Patent no. 12,338,456, issued on June 24, was assigned to HOFFMANN-LA ROCHE INC. (Little Falls, N.J.).

"Method for increasing the specific production rate of eukaryotic cells" was invented by Oliver Popp (Penzberg, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The current invention reports the use of meta-tyrosine for increasing the specific productivity of a eukaryotic cell that produces/expresses a polypeptide. In the current method it is not necessary to perform a temperature-, osmolality- or pH shift or to add drugs like valproic acid or sodium butyrate to modulate the specific productivity of the cultivated cells. The method does not affect cell viabili...