ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,134, issued on June 17, was assigned to Hoffmann-La Roche Inc. (Little Falls, N.J.).

"Trispecific antibodies specific for HER2 and a blood brain barrier receptor and methods of use" was invented by Christian Klein (Bonstetten, Switzerland), Julia Krueger (Munich), Ekkehard Moessner (Kreuzlingen, Switzerland) and Jens Niewoehner (Munich).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to trispecific antibodies binding to HER2 and a blood-brain barrier receptor (BBB-R), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof."

The patent was filed on June 10, 2022, under Appli...